Respirator N95 masks to prevent the inhalation of urban air pollutants

Completed

• Conditions: Air pollution & respiratory problems; Not Applicable; Respiratory disorder, unspecified

• Registration Number: ISRCTN74390617
• Lead Sponsor: niversity of Oxford (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2009-08-04
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Healthy male and female Vietnamese volunteers over 18 years of age

Exclusion Criteria

1. Smoking tobacco
2. Cooking at home with biomass fuel
3. Not willing to stop eating grilled food during study period of 2 weeks
4. Home address is at a main city road
5. Not willing to wear a face mask
6. Type of work prohibits wearing a mask (e.g. regular conversation)
7. No direct access to mobile phone
8. Not able to read or write
9. Not able to complete the study for other reasons
10. Respirator mask does not fit (determined by fitness test)
11. No informed consent

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Concentration of exhaust and smoking metabolites in urine, with 1-hydroxypyrene as the primary endpoint metabolite.<br><br>Outcomes will be measured at day 0 (baseline), day 4, day 7, day 11 and day 14.

Secondary Outcome Measures

Name	Time	Method
Other metabolites in the urine including 1-hydroxynaphthalene, 2-hydroxynaphthalene, 2-hydroxyfluorene, 3-hydroxyfluorene, 9-hydroxyfluorene, 1-hydroxyphenanthrene, 2-hydroxyphenanthrene, 3-hydroxyphenanthrene, 4-hydroxyphenanthrene, Cotinine and Creatinine.<br><br>Outcomes will be measured at day 0 (baseline), day 4, day 7, day 11 and day 14.