A randomised controlled trial to compare conception rates for preconceptional folic acid 400 mg daily versus Pregnacare Plus in assisted conceptio
Completed
- Conditions
- Female infertilityPregnancy and ChildbirthInfertility
- Registration Number
- ISRCTN23488518
- Lead Sponsor
- The Royal Surrey County Hospital NHS Trust (UK)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Female
- Target Recruitment
- 140
Inclusion Criteria
1. Sub-fertile subjects scheduled for In Vitro Fertilisation (IVF) or Intra-Uterine Insemination (IUI)
2. Aged less than 35 years
3. Infertility lasting for greater than six months
Exclusion Criteria
1. Aged greater than 35 years
2. General medical conditions that make a patient unsuitable for assisted conception (i.e. morbid obesity)
3. Women whose understanding of English is insufficient to consent to participation
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie folic acid's impact on conception rates in female infertility?
How does Pregnacare Plus compare to standard folic acid supplementation in assisted conception outcomes?
Are there specific biomarkers that predict response to preconceptional folic acid or Pregnacare Plus in infertility?
What are the potential adverse events associated with high-dose folic acid in assisted conception protocols?
What combination therapies or alternative supplements are being evaluated alongside folic acid for infertility treatment?