A randomised controlled trial to compare conception rates for preconceptional folic acid 400 mg daily versus Pregnacare Plus in assisted conceptio

Completed

• Conditions: Female infertility; Pregnancy and Childbirth; Infertility

• Registration Number: ISRCTN23488518
• Lead Sponsor: The Royal Surrey County Hospital NHS Trust (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2007-07-10
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 140

Inclusion Criteria

1. Sub-fertile subjects scheduled for In Vitro Fertilisation (IVF) or Intra-Uterine Insemination (IUI)
2. Aged less than 35 years
3. Infertility lasting for greater than six months

Exclusion Criteria

1. Aged greater than 35 years
2. General medical conditions that make a patient unsuitable for assisted conception (i.e. morbid obesity)
3. Women whose understanding of English is insufficient to consent to participation

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Survival of assisted conception pregnancy to 20 weeks, or failure to conceive and failure of pregnancy to survive to 20 weeks.

Secondary Outcome Measures

Name	Time	Method
1. Length of pregnancy<br>2. Birth weight (expressed as percentile birth weight in relation to length of pregnancy)<br>3. Abdominal circumference<br>4. Head circumference