NCT00814918撤回不适用
Topical 5-ALA-PDT With Blu-U Therapy Vs. Topical 5-ALA With Pulse Dye Laser In Treatine Recalcitrant Acne Vulgaris
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 1
- 主要终点
- Acne complete /incomplete therapy and reoccurence
研究概览
简要总结
The goal of this study is to compare how efficient two different types of PDTs are when used in combination with topical 5-ALA. The two types of PDT lights are Blu-U light and Candela V-beam Pulse Dye Laser.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 79 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •18-79 years of age
- •Patients who failed the topical and oral antibiotics after 6 month therapy.
- •Patients who failed the topical retinoids after 6 month therapy.
- •Patients that are not good candidate to start oral isotretinoin (Accutane) due to contraindications.
排除标准
- •Patients who have had Isotretinoin therapy less that 1 year prior to this ALA-PDT procedure.
- •Patients who have an adverse reaction to light exposure (for example photo- exacerbated seizures).
- •Patients with a history of porphyria.
研究组 & 干预措施
1
Experimental
5-ALA Application and exposure using Blu-U light to 1/2 of face.
干预措施: 5-ALA with Blu-U Light (Drug)
2
Experimental
5-ALA Application and exposure using Candela V-beam Pulse Dye Laser to 1/2 of face.
干预措施: 5-ALA with Candela V-beam Pulse Dye Laser (Drug)
结局指标
主要结局
Acne complete /incomplete therapy and reoccurence
时间窗: 18 months
次要结局
- Early skin responses 2 weeks post therapy (erythema, scaling, post inflammatory skin changes, fine wrinkling of skin, mottled pigmentation)(2-18 months)
研究者
研究点 (1)
Loading locations...
相似试验
已完成
2 期
Comparative Study Between Topical 5-fluorouracil and Latanoprost in Vitiligo.VitiligoNCT05513924South Valley University40
已完成
2 期
Evaluation of the suitability of a 5-ALA patch (PD P 506 A, Alacare®) in the photodynamic therapy (PDT) of actinic keratosison the upper extremitiesL57.0Actinic keratosisDRKS00015137photonamic GmbH & Co. KG22
尚未招募
4 期
Role of 1 percent topical Spirulina gel as intervention in participants having Oral Lichen PlanusCTRI/2024/06/069548Dr Nitika Aggarwal
已完成
不适用
Comparison of Two Therapeutic Strategies of Dermoval in Treatment of Bullous PemphigusBullous PemphigoidNCT00213421University Hospital, Rouen330
尚未招募
不适用
Efficacy of Topical 5-Fluorouracil Vs Calcipotriol As Photodynamic Therapy Pre-treatment for Field Actinic KeratosesActinic Keratosis of Face and ScalpActinic KeratosesNCT06685588St Vincent's University Hospital, Ireland50