Topical 5-ALA-PDT With Blu-U Therapy Versus Topical 5-ALA With Pulse Dye Laser In Treating Recalcitrant Acne Vulgaris
Not Applicable
Withdrawn
- Conditions
- Acne Vulgaris
- Interventions
- Registration Number
- NCT00814918
- Lead Sponsor
- University of Chicago
- Brief Summary
The goal of this study is to compare how efficient two different types of PDTs are when used in combination with topical 5-ALA. The two types of PDT lights are Blu-U light and Candela V-beam Pulse Dye Laser.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- WITHDRAWN
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
- 18-79 years of age
- Patients who failed the topical and oral antibiotics after 6 month therapy.
- Patients who failed the topical retinoids after 6 month therapy.
- Patients that are not good candidate to start oral isotretinoin (Accutane) due to contraindications.
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Exclusion Criteria
- Patients who have had Isotretinoin therapy less that 1 year prior to this ALA-PDT procedure.
- Patients who have an adverse reaction to light exposure (for example photo- exacerbated seizures).
- Patients with a history of porphyria.
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Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description 2 5-ALA with Candela V-beam Pulse Dye Laser 5-ALA Application and exposure using Candela V-beam Pulse Dye Laser to 1/2 of face. 1 5-ALA with Blu-U Light 5-ALA Application and exposure using Blu-U light to 1/2 of face.
- Primary Outcome Measures
Name Time Method Acne complete /incomplete therapy and reoccurence 18 months
- Secondary Outcome Measures
Name Time Method Early skin responses 2 weeks post therapy (erythema, scaling, post inflammatory skin changes, fine wrinkling of skin, mottled pigmentation) 2-18 months
Trial Locations
- Locations (1)
The University of Chicago
🇺🇸Chicago, Illinois, United States