Randomize clinical trial on determining the effect of Erythromycin on the establishment of feeding in infants under 32 weeks gestation

Iran University of Medical Sciences Research Center0 个研究点目标入组 40 人开始时间: 待定最近更新: 2018年2月22日

适应症

试验速览

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•Infants less than 32 weeks gestational age or weighting less than 1800 g with minimum age of 5 days and clinically stable (Normal blood pressure, not having episodes of bradycardia and hypoxemia); Feeding intolerance for less than 75 milliliters per kilogram per day in 14 days; material remaining in the stomach for more than 50% in 3 hours before, which occurred at least two times during the 24 hours; Vomiting more than 30% of gastric residues in 3 hours that happened at least three times
•Exclusion criteria: Lethal congenital malformations congenital or chromosomal disorders; Cyanotic heart disease; Diseases of the gastrointestinal tract obstruction (Mal rotation, Atresia and Omphalocele, etc.); Gastrointestinal surgeries in 14 days ago; NEC suspected or confirmed in the last 7 days; Definite or clinical sepsis; Metabolic disorders or electrolytic; Treatment with any of the following medications at the onset of feeding intolerance (Fentanyl , Indomethacin, Pancuronioum)

发起方

Iran University of Medical Sciences Research Center