Effect of Denture use on the ability to swallow in individuals with a history of Head and Neck Cancer
- Conditions
- Head and Neck NeoplasmsC06.405.117Swallowing Disorders
- Registration Number
- RBR-6fjfcfg
- Lead Sponsor
- Faculdade de Odontologia de Araçatuba
- Brief Summary
Subjects with a history of head and neck cancer may have dysphagia after treatment, causing physical, psychosocial and emotional impairment. Therefore, the objective of this observational study was to evaluate swallowing in subjects with and without a history of head and neck cancer through electromyographic amplitude, salivary flow and quality of life. Thirty subjects were analyzed, with bimaxillary complete dentures for at least 6 months, with (test group; n=15) and without (control group; n=15) history of head and neck cancer, treated at the Oral Oncology Center of the School of Dentistry of Araçatuba (COB/FOA-UNESP). The electromyographic amplitude of the masseter, temporal and suprahyoid muscles was evaluated during mandibular rest and in the nectar, liquid, pudding and solid swallowing protocols, using a surface electromyograph. Salivary flow was quantified by collecting unstimulated saliva from subjects with complete dentures in position. Dysphagia screening and its effects on quality of life were evaluated using the MD Anderson Dysphagia Inventory (MDADI). The data obtained were submitted to tests of adherence to the normal curve (Shapiro-Wilk) and, subsequently, the appropriate statistical test was applied (T-Student or Mann-Whitney). No statistically significant differences were found between the test and control groups in the electromyographic analysis of the temporal, masseter and suprahyoid muscles in the conditions of rest (p = 0.468 / 0.663 / 0.619) and nectar swallowing (p = 0.240 / 0.830 / 0.870) , liquid (p = 0.101 / 0.760 / 0.838), pudding (p = 0.056 / 0.902 / 0.967) and solid (p = 0.494 / 0.805 / 0.116). Regarding salivary flow, there was also no statistically significant difference between groups (p=0.438). Cancer patients undergoing treatment for head and neck cancer had a great impact on their quality of life, especially for the emotional domain of the applied questionnaire (p<0.001). The evaluation of swallowing through the analysis of the electromyographic amplitude of the masseter, temporal and suprahyoid muscles and salivary flow, however, no statistically significant differences were found between the groups of oncology and non-oncology patients. However, cancer patients undergoing treatment for head and neck cancer had a great impact on their quality of life, especially for the emotional domain of the applied questionnaire.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruitment completed
- Sex
- Not specified
- Target Recruitment
- Not specified
Edentulous individuals who wear bimaxillary dentures for at least 6 months, undergoing treatment for head and neck cancer in the mouth, oropharynx, hypopharynx or larynx will be included.
Individuals with neurological disorders or cognitive alterations will be excluded; with a history of lung diseases; with oral-sinusal or orofacial communication; patients with poorly fitted bimaxillary total dentures or those who do not use them and; individuals without oral use for food.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method It is expected to find out if there is any effect of using bimaxillary complete dentures in the swallowing process of individuals undergoing treatment for head and neck cancer, such as a reduction of at least 50% or improvement in swallowing disorders, such as dysphagia.
- Secondary Outcome Measures
Name Time Method Evaluate, in patients with bimaxillary total dentures undergoing treatment for head and neck cancer. The swallowing process, tracking dysphagia and identifying its effects on quality of life, using the MD Anderson dysphagia questionnaire (MDADI),Classify swallowing or the degree of dysphagia, with and without the use of prostheses, through the protocols for swallowing liquids (V-VST) and chewing and swallowing solids (TOMASS); Salivary flow will be quantified by means of sialometry, with and without the use of prostheses, and the findings will be correlated with the degree of dysphagia and with the clinical-pathological and therapeutic variables found.