The effect of high dose statin therapy (Simvastatin 80 mg) on vascular inflammation in the aortic abdominal aneurysm.

• Conditions: Abdominal Aortic Aneurysm

• Registration Number: NL-OMON25146

Brief Summary

/A

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 25

Inclusion Criteria

1. Abdominal aortic aneurysm;

2. Current statin use.

Exclusion Criteria

1. Liver dysfunction;

2. Excessive alcohol consumption.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Aneurysm wall MCP-1, IL6 and 8 levels.

Secondary Outcome Measures

Name	Time	Method
Aneurysm wall cell content, proteases and inflammatory transcription factors.