Prospective, randomized, double-blind, controlled trial of the healing effect of Polaprezinc for NSAIDs induced small bowel injury.

Not Applicable

• Conditions: SAIDs-induced small bowel injury

• Registration Number: JPRN-UMIN000001538
• Lead Sponsor: Division of Gastroenterology,Department of Internal Medicine, Keio University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2008-12-01
• Study Completion: 2011-03-01
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Not provided

Exclusion Criteria

1) The patients with dysphagia. 2) Pregnant or lactating women. 3) The patients who have history of the ileus or stricture or fistula of the intestine. 4) The patients who have Crohn's disease, Behchet's disease. 5) The patient with pacemaker or other medical electronic equipment. 6) The patient who have taken mucoprotective agent or took it within one month before enrollment. 7) The patient who have severe anemia (less than Hb 8.0mg/dl) or a hematemesis or a melena. 8) The patients who have taken antibiotics or took it within one month before enrollment. 9) The patients who have severe hiatal hernia. 10) The patient who take COX-2 inhibitor (celecoxib) only or low-dose aspirin only. 11) The patients who have severe illness. 12) The patients who have history of abdominal operation or radiation therapy.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Capsule endoscopic findings (number of ulcers/erosions and red spots)

Secondary Outcome Measures

Name	Time	Method
aboratory data and subjective symptom