EUCTR2014-005369-64-ES进行中（未招募）不适用
Improve the myocardial reperfusion in ST elevation myocardial infarction: a randomized study between standard percutaneous coronary intervention with thrombectomy and pharmacological approach guided by the angiographic evidence of thrombus - iBEAST
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •-Chest pain suggestive of myocardial ischemia for at least 30 minutes
- •-Symptoms onset less than 12 hours before hospital admission
- •-ST segment elevation of at least 1 mm in two or more contiguous leads (>o = 2mm in precordial leads)
- •-To understand and accept the study procedures and signed informed consent
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 100
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range 70
排除标准
- •-ST elevation myocardial infarction presenting with cardiogenic shock
- •-Previous myocardial infarction (< 6 months)
- •-Formal contraindication to thrombolysis or to prasugrel
- •-Patients on oral anticoagulation therapy
- •-Patients treated with vitamin K, bivalirudin or fondaparinux
- •-Patients with severe renal failure (glomerular filtration rate <30ml/min/m2)
- •-Patients with contraindication to study medications, which cannot be managed medically, including: adenosine, heparin, IIb-IIIa inhibitors, contrast agents, clopidogrel, ticagrelor, prasugrel or aspirin
- •-Known life-threatening disease with a life expectancy of <12 months
- •-Inability to obtain informed consent
- •-Patients with contraindications to cardiovascular magnetic resonance
- •-Pregnant or breastfeeding patient
- •-Allergic reaction to the product (Methylase) and/or excipient
- •-Patients presenting with pace rhytm, preexcitation or other conditions or artifacts interfering with the interpretation of ST segment resolution
- •-Patient presenting with second or third degree of atrioventricular block or need of temporal pacemarker
- •-Culprit lesion located in small segments or secundary branches <2.5 mm diameter
- •-Impossibility to advance thrombectomy/Amicath device due to extreme tortuosy or calcification
- •-Significant left main disease
- •-Thrombolysis in myocardial infarction (TIMI) flow 3 without the visualization of intracoronary thrombus at initial angiography
研究者
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