Effectiveness of Potassium Supplement in Hypokalemic PD Patients: A Stratified Randomized Controlled Trial

Completed

• Conditions: Hypokalemia in PD patientPeritonitisHospitalizationCardiovascular mortalityAll-cause mortality; Hypokalemia; Peritoneal dialysis; Peritonitis; Potassium supplement

• Registration Number: TCTR20190725004
• Lead Sponsor: Faculty of medicine, Chulalongkorn university

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2019-07-25
• Study Completion: 2021-05-31
• Last Update Posted: 2024-08-19

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 192

Inclusion Criteria

1. End-stage kidney disease on peritoneal dialysis
2. Age 18-80 years.
3. Perform peritoneal dialysis more than 3 months.
4. Serum potassium less than 3.5 mEq/L from previous 6 months (Spotted serum potassium less than 3.5 mEq/L at least 3 visits or time-average serum potassium < 3.5 mEq/L)

Exclusion Criteria

1. Recent peritonitis within 3 months
2. Hybrid with hemodialysis
3. Gastrointestinal tract disease that cannot absorbed potassium supplement.
4. Liver cirrhosis CPS > C
5. Chronic infection/Malignancy/HIV/Pregnancy

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Peritonitis 1 year Time to first peritonitis

Secondary Outcome Measures

Name	Time	Method
Cardiovascular mortality 1 year time to event analysis,All-cause mortality 1 year Time to event analysis,Hospitalization 1 year Time to event analysis,Technique failure 1 year Time to event analysis