NCT06158555招募中不适用
Targeted Perfusion Based Haemodynamic Management in Critically Ill Patients Using Urethral Perfusion - a Pilot Study
King's College Hospital NHS Trust1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2023年4月1日最近更新:
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Change to Urethral Perfusion Index
研究概览
简要总结
To assess the safety and feasibility of the IKORUS device in critically ill patients and to gather exploratory data on haemodynamic coherence
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Within 24 h of ICU admission
- •Predicted length of ICU stay at least 5 days
- •Receiving >0.1 mcg/kg/min of noradrenaline at time of study enrolment
排除标准
- •Palliative treatment intent
- •Contra indication to urethral catheterisation or complication during previous urethral catheter insertion
- •Contraindication to fluid or vasopressor challenges in the opinion of the attending clinician
研究组 & 干预措施
Single Arm
Experimental
Patients will receive fluid and vasopressor challenges and the macro and microvascular responses will be recorded using the IKORUS monitor alongside conventional haemodynamic monitoring
干预措施: 250 ML NaCl 4.5 MG/ML Injection (Drug)
结局指标
主要结局
Change to Urethral Perfusion Index
时间窗: 5 minutes after fluid challenge administration
次要结局
未报告次要终点
研究者
研究点 (1)
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