NCT02219425已完成不适用
Gene Expression Analysis of the Endometrium After Endometrial Biopsy in Fertile Women
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 10
- 试验地点
- 1
- 主要终点
- Gene Expression of the Endometrium after an endometrial biopsy
研究概览
简要总结
The aim of this study is to evaluate the gene expression of the endometrium after an endometrial biopsy in fertile women using Next Generation Sequencing of total RNA.
详细描述
An endometrial biopsy is done at cycle day LH+7 and repeated in the next cycle at cycle day LH+7.
Tissue is analysed and compared for changes in gene expression profile using Seq RNA
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Fertile women
- •Age: 18-40 years
- •BMI: 18-32
- •Regular menstrual cycle
- •No use of hormonal contraceptives or IUD the last 3 months
排除标准
- •Patients in need of a interpreter
- •Suspected intrauterine abnormalities
- •Pregnancy
研究组 & 干预措施
endometrial biopsy
Other
干预措施: endometrial biopsy (Procedure)
结局指标
主要结局
Gene Expression of the Endometrium after an endometrial biopsy
时间窗: 1 month between each biopsy
An endometrial biopsy is done at cycle day LH+7 and repeated in the next cycle at cycle day LH+7. Endometrial tissue is analysed for changes in gene expression profile of various chemokines and cytokines using RNA Sequencing technology
次要结局
未报告次要终点
研究者
研究点 (1)
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