跳至主要内容
临床试验/CTRI/2024/05/066694
CTRI/2024/05/066694尚未招募3 期

An in vivo comparison of clinical efficacy of conventional, nano silver reinforced and fluoride releasing pit and fissure sealants in young permanent molars of children in the age group of 6-9 years

DEVIPRIYA VEGESNA1 个研究点 分布在 1 个国家目标入组 90 人开始时间: 2024年8月5日最近更新:

试验速览

阶段
3 期
状态
尚未招募
发起方
入组人数
90
试验地点
1
主要终点
To compare and evaluate the clinical efficacy of conventional, nano silver reinforced, fluoride releasing pit and fissure sealants by assessing retention, marginal adaptation, surface roughness, color change, fissure caries

研究概览

简要总结

Pit and fissures of the occlusal surfaces of the posterior teeth are more prone to caries development than the smooth surfaces due to their morphological complexity, making dental hygiene more challenging leading to increased plaque accumulation. The enamel in pits and fissures cannot receive the same protection given by fluorides comparing to the enamel in the smooth surfaces. The use of pit and fissure sealants provides a physical barrier that inhibits microorganisms and food particles accumulation, preventing caries initiation, and arresting caries progression. The management of occlusal caries on permanent molars represents a significant challenge because the onset of caries occurs soon after they erupt into the oral cavity. The effectiveness of pit and fissure sealants relays on their long-term retention. This study aims to compare the clinical performance of 3 different pit and fissure sealants (different compositions).

研究设计

研究类型
Interventional
分配方式
Coin toss, Lottery, toss of dice, shuffling cards etc
盲法
Outcome Assessor Blinded

入排标准

年龄范围
6.00 Year(s) 至 9.00 Year(s)(—)
性别
All

入选标准

  • Maxillary and mandibular first permanent molars with deep pits and fissures The entire occlusal surface should be exposed, without the presence of operculum covering the tooth Children whose parents gave consent.

排除标准

  • Teeth with discoloration, restoration, cavitation or developmental defects Partially erupted or erupting teeth are excluded Children who are physically, mentally challenged or with gross orofacial defects or debilitating diseases.

结局指标

主要结局

To compare and evaluate the clinical efficacy of conventional, nano silver reinforced, fluoride releasing pit and fissure sealants by assessing retention, marginal adaptation, surface roughness, color change, fissure caries

时间窗: BASELINE, 4 WEEKS, 12 WEEKS, 24 WEEKS

次要结局

未报告次要终点

研究者

发起方
DEVIPRIYA VEGESNA
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

DR DEVIPRIYA VEGESNA

SRI SAI COLLEGE OF DENTAL SURGERY

研究点 (1)

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