MBCT for Psoriasis Patients With Anxiety and Depression
- Conditions
- Psoriasis
- Interventions
- Behavioral: mindfulness-based cognitive therapy (MBCT)Other: Antipsoriatic treatment
- Registration Number
- NCT05010044
- Brief Summary
This study investigates the effectiveness of a 24-week mindfulness intervention in reducing symptoms in psoriasis patients with anxiety and depression.
- Detailed Description
An adapted MBCT intervention will be offered to people with psoriasis with depression and/or anxiety. 8-week long MBCT therapy will be held between August 2021 and Jan 2022, based on the adapted protocol. The MBCT intervention will consist of 30-minute weekly groups focused on teaching mindfulness techniques and ways to recognize cognitive patterns that can increase anxiety and/or depression. Participants will be recruited from the community, according to the eligibility criteria detailed below. For all participants, anxiety and/or depressive symptom severity(SAS/SDS), PASI,DLQI,(as measured with standardized, validated scales) will be compared baseline and weeks 2;4;8;12;16;20;24. Itch intensity ,itch perception ,quality of sleep, hours missing at work ,helpfulness of common itch therapies serve as the secondary outcome, using a paired t-test.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 60
- the age ranged from 18 to 70 years old
- fulfilled the Classification Criteria for Psoriasis
- the score of the SDS > 50 and / or SAS >50
- Participant has normal or corrected to normal vision and hearing
- Participant is willing and able to give informed consent for participation in the study.
- Participant has insufficient manual dexterity for the computerized tasks
- severe systemic diseases
- patients with severe mental illness or taking psychotic drugs
- Pregnancy
- No access to the internet
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Participants received MBCT once a week for 8 weeks Antipsoriatic treatment Participants received MBCT once a week for 8 weeks. At the same time, the drug therapy for psoriasis was used . Participants received MBCT once a week for 8 weeks mindfulness-based cognitive therapy (MBCT) Participants received MBCT once a week for 8 weeks. At the same time, the drug therapy for psoriasis was used . Active comparator Antipsoriatic treatment Only the drug therapy for psoriasis was used .
- Primary Outcome Measures
Name Time Method Change from Baseline on the Psoriasis Area and Severity Index (PASI) Baseline and Week 2;4;8;12;16;20;24 PASI a measurement that combines severity of lesions and the area affected in one score that ranges from 0 to 72 .
Change from Baseline on the Self-rating Depression Scale (SDS) Baseline and Week 2;4;8;12;16;20;24 In the main component of the SDS , patients are asked 20 questions about Mental and physical feelings of emotional experience, and the patients determine the quality of emotion by selecting one of the options: Occasionally=1, sometimes=2, often=3, and continuously=4.
Change from Baseline on the Dermatology Life Quality Index (DLQI) Baseline and Week 2;4;8;12;16;20;24 The DLQI is a 10-item questionnaire measuring the effect of dermatological diseases on patients over the last week. The DLQI total score is the sum of each individual item score and ranges from 0 or 1 to 30 .
Change from Baseline on the Self-rating Anxiety Scale (SAS). Baseline and Week 2;4;8;12;16;20;24 In the main component of the SAS , patients are asked 20 questions about Mental and physical feelings of emotional experience, and the patients determine the quality of emotion by selecting one of the options: Occasionally=1, sometimes=2, often=3, and continuously=4. The total score is multiplied by an integer of 1.25 to get the standard score.
- Secondary Outcome Measures
Name Time Method Itch perception Baseline Questions regarding situations in which the itch is especially bad (multiple choice options regarding day time, daily situations); objective assessment in which respondents are asked to select answers from the choices offered as a list
Hours missing at work Baseline and Week 2;4;8;12;16;20;24 Approximate average hours missing at work due to itch per week from last visit.
Helpfulness of common itch therapies Baseline and Week 2;4;8;12;16;20;24 Questions regarding helpfulness of common itch therapies.
Trial Locations
- Locations (1)
First Affiliated Hospital of Xi'an Jiaotong University
🇨🇳Xi'an, Shaanxi, China