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Clinical Trials/NCT02438124
NCT02438124
Unknown
Not Applicable

Rhythmic Auditory Stimulation Optimalization for Gait Improvement in Parkinson's

University Hospital, Montpellier3 sites in 1 country80 target enrollmentSeptember 2014

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Parkinson's Disease
Sponsor
University Hospital, Montpellier
Enrollment
80
Locations
3
Primary Endpoint
gait velocity
Last Updated
10 years ago

Overview

Brief Summary

The beneficial effects of rhythmical auditory stimulation (RAS) on spatio-temporal gait characteristics in Parkinson's disease (PD) are attested by clinical research.

Nonetheless, it is still unclear which auditory information parameters (i.e. complexity, temporal regularity or adaptability to gait) maximize the effectiveness of RAS.

Objectives: To evaluate the beneficial effects of RAS on spatio-temporal gait characteristics in PD patients with gait disorders according to:

  • RAS complexity (i.e. metronome, amplitude modulated noise, music)
  • RAS variability (i.e fixed, random, semi-random)
  • RAS adapted in real-time to gait

Variability study:

To study the impact of RAS variability (i.e fixed, random, semi-random) in 20 PD patients and 20 healthy controls on spatio-temporal gait characteristics with metronome, amplitude noise and music.

Adaptability studyTo study the impact of RAS adaptability (i.e fixed, random, adapted in real-time to gait) in 20 PD patients and 20 healthy controls on spatio-temporal gait characteristics with metronome, amplitude noise and music.

Registry
clinicaltrials.gov
Start Date
September 2014
End Date
September 2016
Last Updated
10 years ago
Study Type
Interventional
Study Design
Crossover
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • to be able to understand the study aims and to agree to participate
  • to have signed the consent form
  • to be registered to social security system
  • to reach the diagnosis criteria of idiopathic PD (Queen Square Brain Bank)
  • gait disorder clinically observable

Exclusion Criteria

  • pregnant or lactating woman
  • high probability of non-compliance
  • curators , authorship or advisers to person of full age Specific exclusion criteria for PD patients
  • clinical signs of parkinsonian syndrome
  • Mini Mental State Examination \< 24/30 Specific exclusion criteria for controls
  • neurological disease
  • gait disorder

Outcomes

Primary Outcomes

gait velocity

Time Frame: 2 days

evaluation of walking speed between the different conditions

Secondary Outcomes

  • spatio-temporal gait characteristics(2 days)

Study Sites (3)

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