The effects of two drugs, midazolam and dexmedomidine, in sedation of childre

Phase 2

Recruiting

• Conditions: Other complications of anesthesia; T88.5; Other side effects of anesthesia and sedation.

• Registration Number: IRCT20190522043672N3
• Lead Sponsor: Mashhad University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 13 March 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 180

Inclusion Criteria

Suffering from dysfunction of the central nervous system, whether genetic or acquired

Exclusion Criteria

Having bradycardia
Resistant hypotension during treatment

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The rate of treatment failure and the need for a second sedative drug. Timepoint: The first day, the second day and the third day of the intervention. Method of measurement: Using the Ramsay score table.

Secondary Outcome Measures

Name	Time	Method
Duration of stay in PICU. Timepoint: The day of the patient's discharge. Method of measurement: patient file.;Duration of reaching target sedation. Timepoint: The first, second and third day of the intervention. Method of measurement: Measuring time with a timer.;Duration of mechanical ventilation. Timepoint: The day of the patient's discharge. Method of measurement: patient file.;Bradycardia. Timepoint: daily during the intervention period. Method of measurement: Doctor supervision and clinical monitor.;Hypotension. Timepoint: daily during the intervention period. Method of measurement: Mercury sphygmomanometer.;Mortality rate. Timepoint: The last day of hospitalization. Method of measurement: patient file.