Genetic Association of Glucocorticoid Receptor Gene Polymorphisms With Binge Eating Disorders in Type 2 Diabetic Obese Female Adolescents
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 91
- 试验地点
- 1
- 主要终点
- BED
研究概览
简要总结
The aim of the present study was to specifically screen obese diabetic adolescent female individuals for BED, checking the variants of the GR gene (rs56149945; rs41423247) amongst identified individuals, and this led to assessing the impact of binge eating disorders on glycaemic control in obese diabetic adolescent females in Pakistan, South Asia.
详细描述
Challenges in eating for diabetic adolescents can be categorized as eating disorders (ED) and disordered eating symptoms (DES). Binge-eating disorder (BED) is defined as recurrent episodes of binge eating at least once a week over a three-month time period and it is accompanied by feeling the lack of control and marked distress over one's eating behaviour. The aim of the present study was to specifically screen obese diabetic adolescent female individuals for BED, checking the variants of the GR gene (rs56149945; rs41423247) amongst identified individuals, and this led to assessing the impact of binge eating disorders on glycaemic control in obese diabetic adolescent females in Pakistan, South Asia.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Screening
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 10 Years 至 19 Years（Child, Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Unmarried females diagnosed with Type 2 diabetes > 12 months
- •Age 10-19 years
- •Obesity class I and II (based on BMI range of 30 - 40).
排除标准
- •Presence of psychosis, major psychiatric or neurocognitive disorder
- •Substance use
- •Untreated attention-deficit hyperactivity disorder
- •Use of psychopharmacological medications or psychotherapy
- •Class III obesity
研究组 & 干预措施
Group BED
Those who are diagnosed with having Binge Eating disorder. These individuals qualified after the questionnaire was administered.
干预措施: BED Questionnaire (Diagnostic Test)
Group Non-BED
Those who are not diagnosed with having Binge Eating disorder
结局指标
主要结局
BED
时间窗: Baseline
Presence of BED detected by individuals who score high on the BEDS7 Questionnaire administered
次要结局
- NR3C1 Presence of variants of the GR gene (rs56149945; rs41423247)(Six months into the study after identifying all individuals who scored high on the BEDS7 Questionnaire)
研究者
Dr Zainab Khan
Chief Resident
Corporacion Parc Tauli