Obstructive Sleep Apnea in Scleroderma and Pulmonary Involvement
- Conditions
- Pulmonary DiseaseScleroderma, SystemicSleep Apnea, Obstructive
- Registration Number
- NCT02740569
- Lead Sponsor
- Marmara University
- Brief Summary
Scleroderma is an autoimmune disease with skin manifestations and may have pulmonary involvement. Obstructive sleep apnea (OSA) may also be seen in scleroderma. Less is known regarding the prevalence of OSA in scleroderma and its association with pulmonary involvement.
- Detailed Description
Scleroderma is an autoimmune disease with skin manifestations and may have pulmonary involvement. OSA may also be seen in scleroderma. Less is known regarding the prevalence of obstructive sleep apnea in scleroderma and its association with pulmonary involvement.
The investigators would like to address the prevalence of OSA in patients with Scleroderma, using overnight cardiorespiratory polygraphy. Other comorbidities and pulmonary findings on computer tomography (CT) as well as lung function tests will be evaluated.
The investigators plan to include 60 patients.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 62
- Known scleroderma diagnosis
- Must be able to give informed consent
- Serious neurological and/or psychiatric disease
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Occurrence of OSA defined by apnea-hypopnea index (AHI) of at least 15/h on the overnight sleep study 6 months All participants will be evaluated within 6 months
- Secondary Outcome Measures
Name Time Method Occurrence of pulmonary involvement based on computer tomography findings 6 months All patients will be evaluated within 6 months
Trial Locations
- Locations (1)
Marmara University
🇹🇷Istanbul, Pendik, Turkey