Behandeling van jeukklachten bij brandwondpatiënten met doxepine crème
Completed
- Conditions
- Itch, burns, jeuk, brandwonden
- Registration Number
- NL-OMON25977
- Lead Sponsor
- Prof. E. Middelkoop, PhDAssociation of Dutch Burn CentresZeestraat 27-29, 1941 AJ Beverwijk
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 27
Inclusion Criteria
Age ≥ 18 years
- Healed burns
Exclusion Criteria
- Unable to give informed consent
- Unable to understand and fill in VAS scores and questionnaires (as determined by the treating burn physician)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The main study parameter is the change in pruritus intensity as measured by the Visual Analogue Scale (VAS), with a decrease of ≥2 point being defined as clinically significant.
- Secondary Outcome Measures
Name Time Method The secondary study parameters include the determination of the MIC of the itch scores, the characteristics and impact of itch as measured by the BIQ, and scar quality as measured by the POSAS.<br /><br>Other study parameters include: the use of hydrating cream, use of escape medication and use of pressure garments. Furthermore, we will register sex, age, medical history, cause of burn, location of burn wound, %TBSA burned, time to wound healing (will be estimated retrospectively), % burn wound area that itches, duration of itch, itch before inclusion and wound treatment (conservative or surgery).