Evaluation of the effects of OATP1B1*15 on the plasma concentrations of endogenous compounds (metabolome analysis)
Not Applicable
- Conditions
- healthy male and female
- Registration Number
- JPRN-UMIN000023917
- Lead Sponsor
- Clinical Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Kyushu University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 26
Inclusion Criteria
Not provided
Exclusion Criteria
The investigators must ensure that all subjects being considered meet the following exclusion criteria or conditions: 1) history of allergy to any drugs 2) medical attention within 2 months prior to participation 3) donation of 200 mL or more of blood within 4 weeks prior to participation, or donation of component blood within 2 weeks prior to participation 4) donation of 400 mL or more of blood within 12 weeks prior to participation 5) recent (past 4 months) participation in other clinical trial for investigational new chemical entity 6) history of drug abuse 7) alcohol abuse. 8) lactose intolerance 9) taking drugs or healthy foods which may affect drug metabolism
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method the plasma concentrations of endogenous compounds pharmacokinetics of atorvastatin, pitavastatin, rosuvastatin, and fluvastatin
- Secondary Outcome Measures
Name Time Method