Comparison of Two Mechanical Ventilation Modes on Oxygenisation

Completed

• Conditions: Hypoxia; Bariatric Surgery Candidate; Mechanical Ventilation; Tissue Damage

• Registration Number: NCT04389047
• Lead Sponsor: Bagcilar Training and Research Hospital

Brief Summary

Comparison the effect of two different mechanical ventilation modes on tissue oxygenization.

Detailed Description

Aim of the study is to evaluate and compare the effects of two different mechanical ventilation modes as Volume Controlled Mechanical Ventilation (VCV) and Pressure Controlled Mechanical Ventilation (PCV) on non invasive tissue oxygenization levels of patients who scheduled for bariatric surgery.

Study Timeline

• Study Start: 2012-01-10
• Primary Completion: 2013-03-30
• Study Completion: 2018-03-30
• Study First Submitted: 2020-01-20
• Status Verified: 2020-05
• Study First Submitted QC: 2020-05-11
• Last Update Submitted: 2020-05-11
• Study First Posted: 2020-05-15
• Last Update Posted: 2020-05-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Patients with Body Mass Index 35 - 50 kg/m2 Patients classified as American Society of Anesthesiologist (ASA) 1-2-3 classification Patients elected for Bariatric surgery

Exclusion Criteria

Patients who wants to reject of study participation Patients who has any surgical complication during the surgery period Patients with decompensated cardiac failure Patients with Moderate or Severe obstructive/restrictive lung disease Patients with Reynaud disease Patients with Buerger phenomena Patients whıo has Intraoperative airway pressure more than 45 cmH2O Patients who had previous thoracic surgery Patients with Negative Modified Allen test

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Arterial blood gas analysis	Peroperative 0. minute - 30. minute - 60. minute	Lactate, Ph, Arterial oxygen pressure, Arterial Carbondioxide pressure, Oxygen Saturation
Peripheral oxygen saturation	peroperative 0. minute - 15. minute - 30. minute - 45. minute - 60. minute	Peripheral Oxygen Saturation (SpO2)
Oxygenization-2	post operative 1. hour - 4. hour - 8. hour - 12. hour - 24.hour	Post operative Non invazive technique of Superficial Tissue Oxygenization
Arterial blood gas analysis-2	post operative 1.hour - 4. hour - 8. hour - 12. hour - 24.hour	Lactate, Ph, Arterial oxygen pressure, Arterial Carbondioxide pressure, Oxygen Saturation
Oxygenization	peroperative 0. minute - 15. minute - 30. minute - 45. minute - 60. minute	Peroperative Non invazive technique of Superficial Tissue Oxygenization
Peripheral oxygen saturation-2	post operative 1.hour - 4. hour - 8. hour - 12. hour - 24.hour	Peripheral Oxygen Saturation (SpO2)

Secondary Outcome Measures

Name	Time	Method
Postoperative hemodynamic measurements	post operative 1.hour - 4. hour - 8. hour - 12. hour - 24.hour	Heart rate, Mean Arterial Blood Pressure
Carbondioxide	peroperative 15. minute - 30. minute - 45. minute - 60. minute	End tidal Carbondioxide measurement
Peroperative hemodynamic measurements	peroperative 0. minute - 15. minute - 30. minute - 45. minute - 60. minute	Heart rate, Mean Arterial Blood Pressure