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A0 study to assess safety and effectiveness of carbetocin vs oxytocin after delivery of baby in cesarean section to prevent excessive bleeding

Phase 4
Conditions
Health Condition 1: O82- Encounter for cesarean delivery without indication
Registration Number
CTRI/2024/02/062831
Lead Sponsor
siddaganga medical college and research institute
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

willing to participate

gestational age 36 weeks-41 weeks

patients undergoing cesarean section

Exclusion Criteria

hypertensive

pre eclampsia

eclampsia

ante partum hemorrhage

bleeding disorders

thrombocytopenia

blood coagulation abnormalities

cardiovascular disorders

epilepsy

asthma

migraine

renal disease

liver disease

general anesthesia

retained placenta

placenta accreta

placenta previa

previous pph

grand multipara

fibroid with pregnancy

prolonged labour

hypersensitivity to oxytocin or carbetocin

traumatic pph

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
TO compare the safety and efficacy of carbetocin with oxytocin to prevent PPH during active management of third stage of labour.Timepoint: blood loss assesment intraoperatively,at 1st hour, 2nd hour post partum, 8th hour, 14th hour, 20th hour, 26th hour.
Secondary Outcome Measures
NameTimeMethod
To compare adverse effects among both groups.Timepoint: adverse effects noted intraoperatively,at 1st hour, 2nd hour post partum, 8th hour, 14th hour, 20th hour, 26th hour.;To compare the requirement for additional uterotonics in both groupsTimepoint: need for additional uterotonics assesed intraoperatively,at 1st hour, 2nd hour post partum, 8th hour, 14th hour, 20th hour, 26th hour.
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