NL-OMON55211招募中不适用
Quantitative-imaging in cardiac transthyretin amyloidosis (I-CARE) - i-CARE
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 70
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Completion of informed consent • Age > 18 years • ATTR cardiac amyloid
- •according to Expert Consensus Recommendations • AL amyloidosis according to
- •Expert Consensus Recommendations • Hypertrophic cardiomyopathy according to
- •European Society of Cardiology guidelines
排除标准
- •Inability or unwilling to give informed consent
- •Women who are pregnant, breastfeeding or of child-bearing potential (women
- •experienced menarche, are pre-menopausal and have not been sterilised)
- •will not be enrolled
- •into the trial.
- •Renal dysfunction (eGFR <=30 mL/min/1.73m2)
- •NYHA Class IV heart failure
- •Patients with atrial fibrillation and poor rate control.
- •Contraindications to MR
- •Previous history of contrast allergy of adverse reactions (gadolinium)
- •Contraindications to Tafamidis therapy
- •With regards to patient exclusion for solely 1[23I]MIBG scan:
- •Tricyclic antidepressants (TCA) usage (most importantly amitriptyline,
- •clomipramine, imipramine, nortriptyline, chlorpromazine or perphenazine);
- •Parkinson*s disease as mentioned in patients* medical history;
- •Insulin dependent diabetes mellitus as shown in patients* actual medication
研究者
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