Heart protection study

Medical Research Council (MRC) (UK)0 个研究点目标入组 20,000 人开始时间: 2000年4月6日最近更新: 2015年1月13日

适应症

试验速览

暂无简介。

•1. Patients at high risk of CHD (e.g., because of history of vascular disease or diabetes)
•2. Without clear indication for or contra-indication to statin
•3. Male and female adults
•4. Non-fasting blood total cholesterol concentrations of at least 3.5 mmol/L (135 mg/dL)

•1. The patient's doctor considered statin therapy to be clearly indicated or contra-indicated
•2. A past history of: stroke, myocardial infarction or angina hospitalisation within the previous six months
•3. Chronic liver disease or evidence of abnormal liver function
•4. Severe renal disease or evidence of substantially impaired renal function
•5. Inflammatory muscle disease or evidence of muscle problems
•6. Concurrent treatment with cyclosporin, fibrates or high-dose niacin
•7. Child-bearing potential
•8. Severe heart failure
•9. Life-threatening conditions other than vascular disease or diabetes (including any cancer except non-melanoma skin cancer)
•10. Any other condition that might limit long-term compliance

发起方

Medical Research Council (MRC) (UK)