A comparative evaluation of oxygen releasing gel and vitamin E on post operative outcomes after surgical gingival depigmentation. A split mouth clinical study.
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 12
- 试验地点
- 1
研究概览
简要总结
This split-mouth clinical study will evaluate and compare topical oxygen-releasing gel and Vitamin E on postoperative pain and gingival healing following surgical gingival depigmentation, using the Visual Analog Scale (VAS) and Dummett–Gupta Oral Pigmentation Index. Oxygen-releasing gel works by supplying sustained oxygen to the surgical site, enhancing cellular activity, promoting collagen formation, supporting angiogenesis, and reducing anaerobic bacterial load, thereby aiding wound healing. Vitamin E acts as an antioxidant, reducing oxidative stress, stabilizing cell membranes, and supporting epithelial regeneration and tissue repair. The study will compare their effectiveness in improving postoperative comfort and gingival healing.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 35.00 Year(s)（—）
- 性别
- All
入选标准
- •Gingival melanin hyperpigmentation in maxillary and/ or mandibular arches.
- •Participants willing to undergo surgical depigmentation.
排除标准
- •Participants unable/unwilling to undergo surgical procedure.
- •Participants with the habit of smoking.
- •Pregnant and lactating women.
- •Medically compromised participants.
- •Those with a history of periodontal surgery in less than 3 months.
- •Those with gingival pigmentation associated with other syndromes and lesions.
- •Hypersensitivity to Vitamin E.
研究者
Haripriya H R
Sri Hasanamba dental college and hospital