Investigation of the Effects of Upper Extremity Botulinum Toxin Application on Forearm Muscle Thickness and Motor Recovery in Patients With Hemiplegia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Muscle Thickness
研究概览
简要总结
In this study, we aimed to examine the effects of the botulinum toxin (BoNT) application on muscle thickness and motor recovery in stroke patients.
详细描述
Stroke is the second leading cause of death worldwide. It poses a major risk for disability. Its prevalence is high in developing countries. Spasticity is among the complications of stroke. Excessive spasticity can cause impairments and limitations in patients' motor activity and participation in daily life. Botulinum toxin (BoNT) injection is one of the preferred treatment options. Studies on botulinum toxin administration in stroke patients generally focus on treatment efficacy and motor recovery. Studies examining the effects of botulinum toxin administration on both muscle thickness and motor recovery are few in number. In this study, we aimed to examine the effects of the botulinum toxin (BoNT) application on upper extremity muscle thickness and motor recovery in stroke patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 30 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients must be between the ages of 30-
- •Patients who received botulinum toxin injection to their upper extremities at least 3 months after a cerebrovascular accident.
- •Patients must have had cerebrovascular disease for the first time.
排除标准
- •Presence of a preexisting musculoskeletal deformity in the upper extremity where botulinum toxin was administered
- •Patients with spinal cord injury, multiple sclerosis, and cerebral palsy
- •Presence of malignancy.
结局指标
主要结局
Muscle Thickness
时间窗: 4 week after treatment
Muscle thickness measurements were performed using a Falcon 2101 EXL 2003 ultrasound device equipped with an 8 MHz linear probe, both before and one month after botulinum toxin application. In patients who received botulinum toxin injections into the m. brachialis, m. pronator teres, m. flexor carpi radialis, m. flexor carpi ulnaris, m. flexor digitorum profundus, and m. flexor digitorum superficialis, muscle thickness was measured using ultrasound from the proximal one-third of the volar side of the forearm. Measurements were taken before and one month after the application. Muscle thickness was recorded by measuring the vertical distance between the subcutaneous tissue and the radius and ulna bone borders on the ultrasound image.
Brunnstrom Motor Recovery Stages
时间窗: 4 week after treatment
Brunnstrom stages is a scale used to assess motor recovery after a stroke, which is expressed using values between 1 and 6. The higher the value on this scale, the higher would be the recovery.
次要结局
- Modified Ashworth Scale(4 week after treatment)
研究者
Serdar Kilinc
assistant professor
Abant Izzet Baysal University