SPECT Fibroblast Activation Protein Imaging in Patients With Cardiac Disease
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 50
- 主要终点
- positive uptake
研究概览
简要总结
This observational study aims to learn about the preliminary exploration of 99mTc-FAPI imaging in heart diseases and its potential application.
Participant involves patients with myocarditis, pulmonary hypertension, arrhythmia, myocardial infarction, dilated cardiomyopathy, and cardiac tumors, health conditions may also studied as control.
The main questions it aims to answer are 1, radionuclide 99mTc labeled fibroblast-activated protein inhibitors (99mTc-FAPI) imaging in the use of cardiac diseases and its limitations. 2, the performance in subjects with different control of hypertension to evaluate myocardial injury and fibrosis for providing a molecular biological basis for the study of diseases and mechanisms.
Participants will undergo 99mTc-FAPI imaging by Single-photon emission computed tomography (SPECT) and record their cardiac disease characterization and treatment.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Clinical diagnosis or suspected of cardiac injury
- •Must be able to receive PET/CT scan
排除标准
- •Pregnant women
- •Severe claustrophobia
结局指标
主要结局
positive uptake
时间窗: 3 months
99mTc-FAPI accumulation on the heart, measure the standardized uptake values (SUV)
次要结局
未报告次要终点