Effectiveness of Ultrasound Guided PECS Block on Opioid Consumption and Patient Satisfaction Through Adequate Pain Control Following Breast Cancer Surgery. A Prospective Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 70
- 试验地点
- 1
- 主要终点
- Total intraoperative opioid consumption
研究概览
简要总结
Breast cancer is the most common and leading cause of cancer deaths among females worldwide. Patients undergoing modified radical mastectomy (MRM) are associated with moderate to severe acute postoperative pain and shoulder mobility restriction.
This study aims to determine the effectiveness of ultrasound-guided PECS block for reducing opioid consumption, providing adequate postoperative pain management and improving patient satisfaction following breast cancer surgery.
详细描述
The traditional pain management for patients undergoing MRM has relied heavily on opioids but a number of multimodal pain control strategies also exist including combining opioids with NSAIDs, cyclooxygenase-2 inhibitors, acetaminophen and regional blocks. Recently, literature underlines the importance of performing regional anaesthetic and analgesic techniques for postoperative analgesia following breast surgery. PECS (Pectoral nerve block) block provides analgesia for breast surgeries with few adverse effects.
OBJECTIVES To evaluate the effect of ultrasound guided pectoral block in reducing intraoperative and postoperative opioid consumption following modified radical mastectomy.
The secondary objective is to determine patient satisfaction levels associated with adequate pain control.
HYPOTHESIS Pectoral nerve blocks provides superior analgesia with less opioid consumption and improves patient satisfaction in postoperative period compared to conventional pain management for modified radical mastectomy patients
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Patients undergoing elective modified radical mastectomy (MRM)
- •All adults aged between 18 and 65 years
- •ASA (American Society of Anesthesiologists ) I & II
排除标准
- •Patient refusal
- •Hypersensitivity to local anaesthetics
- •Coagulopathy or bleeding diathesis
- •Local infection at the site of block
- •BMI more than 35 kg/m2
- •Chest wall deformity or previous breast surgery
- •MRM with latissimus dorsi or deep inferior epigastric perforator flap reconstruction
结局指标
主要结局
Total intraoperative opioid consumption
时间窗: During surgical procedure
Total intraoperative nalbuphine
Total postoperative opioid consumption
时间窗: First 24 hours after surgery
Total Rescue Tramadol Consumption
次要结局
- Patient Satisfaction(First 24 hours after surgery)
- Postoperative pain score(1, 6,12 and 24 hours after surgery)
- Postoperative nausea and vomiting(First 24 hours after surgery)
研究者
Faisal Shamim
Associate Professor Anaesthesiology
Aga Khan University