JPRN-UMIN000049311已完成Unknown
Effect of brexpiprazole on sleep architecture in patients with schizophrenia - Effect of brexpiprazole on sleep architecture in patients with schizophrenia
Department of Psychiatry, Kurita Hospital0 个研究点目标入组 7 人开始时间: 2022年10月25日最近更新:
适应症
试验速览
- 阶段
- Unknown
- 状态
- 已完成
- 发起方
- 入组人数
- 7
研究概览
简要总结
Add-on brexpiprazole had the following effects on sleep architecture in patients with schizophrenia. The fraction of stage N2 increased by 14.0% (p = 0.018), and the duration increased by 49.9 min (p = 0.018). The fraction of stage N3 increased by 0.7% (p = 0.027), and the duration increased by 2.5 min (p = 0.034). Additionally, the fraction of stage REM sleep was reduced by 10.0% (p = 0.018), and the duration was decreased by 33.8 min (p = 0.018).
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- ot applicable 至 ot applicable（—）
- 性别
- All
入选标准
- 未提供
排除标准
- •1.Comorbidity with mood disorder, anxiety disorder, drug addiction, personality disorder 2.Comorbidity with serious physical diseases such as cerebrovascular disease, heart disease, renal dysfunction, neurological disease 2.Comorbidity with sleep disorders such as hypersomnia, sleep-related breathing disorders, circadian rhythm sleep disorders, parasomnias, and sleep-related movement disorders 3. Use of drugs that affect sleep electroencephalography (EEG), such as hypnotics, anxiolytics, mood stabilizers, antihistamines, steroids, etc. 4.Apnea Hypopnea Index (AHI) > 15/h; and Periodic Limb Movement Index (PLMI) > 15/h.
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