Short term clinical efficacy and safety of Tolvaptan additional treatment compared with escalation treatment of conventional diuretics in HF patients with volume overload despite treatments with the conventional diuretics
- Conditions
- congestive heart failure
- Registration Number
- JPRN-UMIN000009136
- Lead Sponsor
- Kyoto University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 40
Not provided
Patients with a history of hypersensitivity for an ingredient of tolvaptan or an analogue (Mozavaptan) Patients with anuria Patients who cannot feel thirst or are difficult to intake the fluid. Patients with hypernatremia. Female patients who are pregnant, possibly pregnant, or lactating, or who plan to become pregnant. Patients who are diagnosed following diseases A)Serious coronary artery disease, cerebrovascular disease B)Hyperkalemia C)Serious Renal failure D)Diabetes mellitus with poorly controlled blood glucose E)Serious hepatic disorder F)Urinary excretion disorder in order to the stenosis of the urinary tract G)Valvular disease that in order to valvular stenosis is severe H)Malignant tumor Patients otherwise judged by the investigator or subinvestigator to be inappropriate for inclusion in the study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method