NCT00006119已完成2 期
Phase II Study of Hydroxyurea for the Treatment of Recurrent and/or Nonoperable Meningioma
适应症
相关药物
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- UNICANCER
- 试验地点
- 10
研究概览
简要总结
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.
PURPOSE: Phase II trial to study the effectiveness of hydroxyurea in treating patients who have recurrent and/or unresectable meningioma.
详细描述
OBJECTIVES:
- Determine complete, partial, or stable response to hydroxyurea in patients with recurrent and/or nonresectable meningioma.
- Determine response at 2 years to this regimen in these patients.
- Determine overall and disease free survival of these patients after this regimen.
- Determine quality of life of these patients.
- Determine the toxicities of this regimen in these patients.
OUTLINE: This is a multicenter study. Patients are stratified according to grade of disease (I vs II or III).
Patients receive oral hydroxyurea daily for 2 years.
Quality of life is assessed before treatment, then every 3 months for 2 years.
研究设计
- 研究类型
- Interventional
- 主要目的
- Treatment
入排标准
- 年龄范围
- 16 Years 至 120 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
研究者
研究点 (10)
Loading locations...
相似试验
已完成
2 期
S9811 Hydroxyurea in Treating Patients With Unresectable Benign MeningiomaAdult MeningiomaNCT00003590SWOG Cancer Research Network29
Unknown
1 期
Hydroxyurea Plus Combination Chemotherapy in Patients With Non-small Cell Lung CancerLung CancerNCT00002887Ottawa Regional Cancer Centre30
已完成
2 期
Hydroxyurea in Treating Patients With Epstein-Barr Virus-Associated Primary CNS Lymphoma and AIDSLymphomaNCT00002940St. Jude Children's Research Hospital
已完成
2 期
Chemotherapy Plus Peripheral Stem Cell Transplant in Treating Patients Who Have Multiple Myeloma or Primary Systemic AmyloidosisMultiple Myeloma and Plasma Cell NeoplasmNCT00007995Herbert Irving Comprehensive Cancer Center75
已完成
2 期
Combination Chemotherapy in Treating Patients With Liver Metastases From Colorectal CancerMetastatic CancerColorectal CancerNCT00003834Alliance for Clinical Trials in Oncology44