ight therapy exploratory trial: investigating the effectiveness and feasibility of home use light therapy for the management of depressio

Not Applicable

Completed

• Conditions: Mild - moderate depression; Mental and Behavioural Disorders; Depression

• Registration Number: ISRCTN11848158
• Lead Sponsor: niversity of Kent

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-02-02
• Study Completion: 2016-05-01
• Last Update Posted: 4 December 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1. Aged 18 to 64 years old
2. Current diagnosis of mild-moderate depression defined via a PHQ-9 score of 5 to 14
3. Ability to provide informed consent for randomisation, treatment and follow up, including a good command of the English language
4. Ability to access their general practice surgery / University campus at Medway for assessment

Exclusion Criteria

1. Pregnant/planning pregnancy or breastfeeding
2. Alterations to participant antidepressant treatment, including medication and counselling/talk therapy, in the previous four weeks of trial commencement or during the trial
3. Current treatment with antipsychotic drugs
4. Previous use of light therapy, including use of light boxes, light visors and dawn simulation lamps. This does not include the use of seasonal affective disorder (SAD) alarm clocks
5. History of or current substance/drug abuse
6. History or current diagnosis of; psychosis, severe depression, bipolar disorder, Parkinson’s, dementia or Alzheimer’s disease.
7. A history of light-induced migraine or epilepsy
8. A history of traumatic brain injury (TBI)
9. Presence of ocular disorders including retinal blindness, cataract, retinal diseases of the eye and glaucoma.
10. Current oral diseases, such as candidiasis, or inflammation or lesions within the mouth
11. Is currently or has recently been involved in any research prior to this study

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<br> Response to treatment at four weeks of the intervention as compared to baseline, measured by the Structured Interview Guide for the Hamilton Depression Rating Scale – Seasonal Affective Disorder version Self-rated (SIGH-SAD-SR).<br><br> The resulting SIGH-SAD score will be treated in two ways. A total SIGH-SAD-SR score of less than or equal to 50% of the baseline total score will be used to define response”. A total SIGH-SAD-SR score less than or equal to 50% of the baseline total score, and a total score of less than or equal to 8 will be used to define remission”. These parameters provide a quantitative measurement of improvement and estimate participant recovery.<br>