Effectiveness of Ivermectin on Outpatient Treatment of Covid-19 Patients

Phase 3

Recruiting

• Conditions: Covid-19 disease.; Covid-19; U07.1

• Registration Number: IRCT20210213050344N1
• Lead Sponsor: Shiraz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 26 April 2021

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 375

Inclusion Criteria

Clients to selected outpatient treatment centers in Shiraz
Only mild symptoms and clinical manifestations (including: fever less than 38 degrees, sore throat with or without dry cough, chills, headache, loss of taste and smell, nausea, vomiting, anorexia, diarrhea, body aches, weakness and Excessive fatigue, persistent yard symptoms)
Positive RT-PCR test result
Age between 18 and 80 years
People with underlying disease (to evaluate the effectiveness of the drug on people with underlying disease)
Individuals who have completed and signed the written consent to participate in the project
Blood oxygen level 93% and above (O2 sat = 93%)

Exclusion Criteria

Pregnant mothers
Breastfeeding mothers
Severe liver disease
Severe kidney disease
Severe lung disease
HIV Positive patients
Chronic obstructive pulmonary disease (COPD)
Participate in another RCT
Dissatisfaction with participating in the study

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The trend of clinical symptoms of Covid-19 disease. Timepoint: Seven time periods on days: Zero, 1, 3, 7, 14, 21 and 28. Method of measurement: Clinical information by completing a qualitative questionnaire and conduct interviews and observations.;Blood oxygen level (O2 Saturation). Timepoint: Seven Time Periods on Days: Zero, 1, 3, 7, 14, 21 and 28. Method of measurement: Pulse oximeter device.;Hospitalization. Timepoint: Seven time periods on days: Zero, 1, 3, 7, 14, 21 and 28. Method of measurement: Clinical information by completing a qualitative questionnaire and observation.;Requires intubation or ICU. Timepoint: Seven time periods on days: Zero, 1, 3, 7, 14, 21 and 28. Method of measurement: Clinical information by completing a qualitative questionnaire and observation.;Death. Timepoint: Seven time periods on days: Zero, 1, 3, 7, 14, 21 and 28. Method of measurement: Clinical information by completing a qualitative questionnaire and observation.