Comparison of two different doses of thiopental sodium in elective cesarean section (C/S) under general anesthesia on depth of anesthesia with Isolated Forearm Technique (IFT) and on neonatal neurobehavioral test

Phase 2

Conditions: caesarean section.
Delivery by elective caesarean section

Registration Number: IRCT2016082819470N45

Lead Sponsor: Shiraz University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: Female

Target Recruitment: 80

Inclusion Criteria

Aged between 15-50
pregnant women undergoing cesarean section
ASA I-II

Exclusion Criteria

Patients who are not properly cooperate
Prior use of sulfate MgSO4
Mental disorders
History of previous awareness during general anesthesia
Taking blood pressure medication or vasodilators or vasodepressor and human stimulant or psychotropic drugs
Neuromuscular diseases
Opium addiction
Fetal abnormalities by ultrasonography

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To determine the depth of the anesthesia by Sodium Thiopental and Propofol as an induction anesthetic. Timepoint: at baseline, Induction of anesthesia, laryngoscopy and intubation, Skin incision, opening the peritoneum, Uterine incision, uterine retraction, childbirth, Uterine closure, tying the layers under the skin, Subcutaneous closures, at the start of skin closure,2 minutes after skin closure, eye opening and extubation. Method of measurement: Bispectral index (BIS) and Isolated forearm technique (IFT.

Secondary Outcome Measures

Name	Time	Method
eonate Apgar. Timepoint: at 0, 5, and 20 minutes after birth. Method of measurement: Apgar score.;Neurobehavioral test. Timepoint: 20 minutes after birth. Method of measurement: Neurobehavioral test.