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Clinical Trials/NCT00012493
NCT00012493
Completed
Not Applicable

Cardiac Vulnerability in Potentially Susceptible Patients

National Institute of Environmental Health Sciences (NIEHS)1 site in 1 country100 target enrollmentOctober 1999
ConditionsHeart Disease

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Heart Disease
Sponsor
National Institute of Environmental Health Sciences (NIEHS)
Enrollment
100
Locations
1
Status
Completed
Last Updated
19 years ago

Overview

Brief Summary

This project is part of a program project directed toward assessing cardiac effects of particulate and other ambient air pollutants. In this project patient who have recently suffered a cardiac event are being monitored with cardiac monitors for 24 hours up to 4 times during the year following their cardiac event. Similarly a second group of patients with moderate to severe heart failure will undergo similar cardiac monitoring for 24 hours, twice a week separated by 3 months. In both sets of patients home indoor pollution measures will be continuously made and used to correlate with measures of heart rate variability.

Detailed Description

Approximately 50 patients in each group will be studied. In addition to cardiac monitoring for 24 hours at each session, overnight respiratory pattern and oxygen saturation will be monitored in both groups. The exposure monitoring will include both particle mass of PM2.5 along with detailed assessment to determine that portion of the particulate exposure from outdoor vs. indoor sources.

Registry
clinicaltrials.gov
Start Date
October 1999
End Date
December 2002
Last Updated
19 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
National Institute of Environmental Health Sciences (NIEHS)

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Not specified

Study Sites (1)

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