Comparing Postoperative Pain After Pericapsular Nerve Block and Fascia Iliaca Block in Total Hip Arthroplasty

Not Applicable

Recruiting

• Conditions: Anesthesia
• Interventions: Procedure: fascia iliaca compartment block; Procedure: pericapsular nerve block; Procedure: palcebo pericapsular nerve block; Procedure: palcebo fascia iliaca compartment block

• Registration Number: NCT06003738
• Lead Sponsor: Ain Shams University

Brief Summary

The aim of this study is to investigate the efficiency of post-operative analgesia by fascia iliaca compartment block versus pericapsular nerve group block block in reducing narcotic consumption during the first 24 hour post-operatively by using the Visual Analogue Scale.

Detailed Description

Total hip arthroplasty is a widely used surgical treatment intervention for treating hip conditions such as femur neck fractures and advanced hip osteoarthritis.

Hip fractures are quite common, regardless of the age of the population (young or old), and they are extremely painful. A hip fracture is a serious injury with potentially life-threatening complications, and it is a common orthopedic emergency in elderly individuals. Early surgery within 48 hours of a fracture has been found to lower mortality and complication rates.

The pericapsular nerve group block is a novel regional analgesia technique to decrease pain after THA while preserving the motor function. The local anaesthetic is deposited using this method in the fascial plane between the psoas muscle and the superior pubic ramus, which aims sensory branches of the obturator, accessory obturator, and femoral nerves in the anterior capsule of the hip.

Fascia iliaca compartment block, for procedures on the femur and hip joint, is still a well-liked regional anaesthetic technique. Studies have found that FICB prevents complications by anaesthetizing the femoral nerve far from critical neurovascular structures while still giving enough analgesia.

Both blocks could be used to effectively reduce pain intensity up to 24 hours, total opioid consumption, and length of hospital stay in THA patients.

Study Timeline

• Study First Submitted: 2023-07-12
• Status Verified: 2023-08
• Study First Submitted QC: 2023-08-15
• Study Start: 2023-08-21
• Last Update Submitted: 2023-08-21
• Study First Posted: 2023-08-22
• Last Update Posted: 2023-08-23
• Primary Completion: 2024-08-21
• Study Completion: 2024-09-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 68

Inclusion Criteria

1. Age 18-80 years.
2. Sex: Both sexes.
3. American Society of Anaesthesiologists (ASA) Physical Status Class I, II, and III.
4. Scheduled for Total hip arthroplasty (THA) under spinal anesthesia.

Exclusion Criteria

1. Declining to give a written informed consent.
2. History of allergy to the medications used in the study.
3. Contraindications to regional anesthesia (including patient refusal, coagulopathy, and local infection).
4. Psychiatric disorders.
5. Significant cognitive dysfunction.
6. American Society of Anesthesiologists (ASA) Physical Status Class IV.
7. Liver failure, renal insufficiency (estimated glomerular filtration rate < 15 mL/min/1.73 m2).
8. Patients who had failed spinal anaesthesia were excluded from the study.
9. Pregnancy.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
The fascia iliaca compartment block group	fascia iliaca compartment block	The first group 34 patients
The pericapsular nerve block group	pericapsular nerve block	The second group 34 patients
The fascia iliaca compartment block group	palcebo pericapsular nerve block	The first group 34 patients
The pericapsular nerve block group	palcebo fascia iliaca compartment block	The second group 34 patients

Primary Outcome Measures

Name	Time	Method
The effect of the studied blocks on the Visual Analogue Scale for pain	Immediately postoperatively (zero time)	the Visual Analogue Scale for pain is ranging from 0 to 10, where 0 is no pain and 10 is maximum pain
Change in the Visual Analogue Scale for pain	every 6 hours in the first 24 hours postoperatively	the Visual Analogue Scale for pain is ranging from 0 to 10, where 0 is no pain and 10 is maximum pain

Secondary Outcome Measures

Name	Time	Method
Mean arterial blood pressure change	24 hours postoperatively	hemodynamics
The total dose of nalbuphine in mg was used postoperatively per patient	24 hours postoperatively	rescue analgesia
Heart rate change	24 hours postoperatively	hemodynamics

Trial Locations

Locations (1)

Ain shams university hospitals; 🇪🇬 Cairo, Egypt