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Clinical Trials/NCT06003738
NCT06003738
Recruiting
N/A

A Comparative Study Between the Postoperative Analgesic Effect of Pericapsular Nerve Group Block (PENG) and Fascia Iliaca Compartment Block (FICB) in Total Hip Arthroplasty: a Prospective Randomized Clinical Trial

Ain Shams University1 site in 1 country68 target enrollmentAugust 21, 2023
ConditionsAnesthesia

Overview

Phase
N/A
Intervention
Not specified
Conditions
Anesthesia
Sponsor
Ain Shams University
Enrollment
68
Locations
1
Primary Endpoint
The effect of the studied blocks on the Visual Analogue Scale for pain
Status
Recruiting
Last Updated
2 years ago

Overview

Brief Summary

The aim of this study is to investigate the efficiency of post-operative analgesia by fascia iliaca compartment block versus pericapsular nerve group block block in reducing narcotic consumption during the first 24 hour post-operatively by using the Visual Analogue Scale.

Detailed Description

Total hip arthroplasty is a widely used surgical treatment intervention for treating hip conditions such as femur neck fractures and advanced hip osteoarthritis. Hip fractures are quite common, regardless of the age of the population (young or old), and they are extremely painful. A hip fracture is a serious injury with potentially life-threatening complications, and it is a common orthopedic emergency in elderly individuals. Early surgery within 48 hours of a fracture has been found to lower mortality and complication rates. The pericapsular nerve group block is a novel regional analgesia technique to decrease pain after THA while preserving the motor function. The local anaesthetic is deposited using this method in the fascial plane between the psoas muscle and the superior pubic ramus, which aims sensory branches of the obturator, accessory obturator, and femoral nerves in the anterior capsule of the hip. Fascia iliaca compartment block, for procedures on the femur and hip joint, is still a well-liked regional anaesthetic technique. Studies have found that FICB prevents complications by anaesthetizing the femoral nerve far from critical neurovascular structures while still giving enough analgesia. Both blocks could be used to effectively reduce pain intensity up to 24 hours, total opioid consumption, and length of hospital stay in THA patients.

Registry
clinicaltrials.gov
Start Date
August 21, 2023
End Date
September 1, 2024
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Diaaeldin Badr Aboelnile

Lecturer of Anesthesia

Ain Shams University

Eligibility Criteria

Inclusion Criteria

  • Age 18-80 years.
  • Sex: Both sexes.
  • American Society of Anaesthesiologists (ASA) Physical Status Class I, II, and III.
  • Scheduled for Total hip arthroplasty (THA) under spinal anesthesia.

Exclusion Criteria

  • Declining to give a written informed consent.
  • History of allergy to the medications used in the study.
  • Contraindications to regional anesthesia (including patient refusal, coagulopathy, and local infection).
  • Psychiatric disorders.
  • Significant cognitive dysfunction.
  • American Society of Anesthesiologists (ASA) Physical Status Class IV.
  • Liver failure, renal insufficiency (estimated glomerular filtration rate \< 15 mL/min/1.73 m2).
  • Patients who had failed spinal anaesthesia were excluded from the study.

Outcomes

Primary Outcomes

The effect of the studied blocks on the Visual Analogue Scale for pain

Time Frame: Immediately postoperatively (zero time)

the Visual Analogue Scale for pain is ranging from 0 to 10, where 0 is no pain and 10 is maximum pain

Change in the Visual Analogue Scale for pain

Time Frame: every 6 hours in the first 24 hours postoperatively

the Visual Analogue Scale for pain is ranging from 0 to 10, where 0 is no pain and 10 is maximum pain

Secondary Outcomes

  • Mean arterial blood pressure change(24 hours postoperatively)
  • The total dose of nalbuphine in mg was used postoperatively per patient(24 hours postoperatively)
  • Heart rate change(24 hours postoperatively)

Study Sites (1)

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