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临床试验/NCT06003738
NCT06003738已完成不适用

Postoperative Analgesia After Total Hip Arthroplasty: Comparative Evaluation of Pericapsular Nerve Group Versus Fascia Iliaca Compartment Block in a Randomized Controlled Trial

Ain Shams University1 个研究点 分布在 1 个国家目标入组 68 人开始时间: 2023年9月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
68
试验地点
1
主要终点
Number of cases needing rescue doses

研究概览

简要总结

The aim of this study is to compare the effectiveness of pericapsular nerve group (PENG) block versus fascia iliaca compartment block (FICB) for postoperative pain relief following total hip arthroplasty (THA).

详细描述

Total hip arthroplasty is a widely used surgical treatment intervention for treating hip conditions such as femur neck fractures and advanced hip osteoarthritis.

Hip fractures are quite common, regardless of the age of the population (young or old), and they are extremely painful. A hip fracture is a serious injury with potentially life-threatening complications, and it is a common orthopedic emergency in elderly individuals. Early surgery within 48 hours of a fracture has been found to lower mortality and complication rates.

The pericapsular nerve group block is a novel regional analgesia technique to decrease pain after total hip arthroplasty (THA) while preserving the motor function. The local anaesthetic is deposited using this method in the fascial plane between the psoas muscle and the superior pubic ramus, which aims sensory branches of the obturator, accessory obturator, and femoral nerves in the anterior capsule of the hip.

Fascia iliaca compartment block, for procedures on the femur and hip joint, is still a well-liked regional anaesthetic technique. Studies have found that FICB prevents complications by anaesthetizing the femoral nerve far from critical neurovascular structures while still giving enough analgesia.

Both blocks could be used to effectively reduce pain intensity up to 24 hours, total opioid consumption, and length of hospital stay in THA patients.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Double (Participant, Outcomes Assessor)

入排标准

年龄范围
18 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • •Age from 18 to 80 years.
  • •Both sexes.
  • •American Society of Anaesthesiologists (ASA) Physical Status II-III.
  • •Scheduled for Total hip arthroplasty (THA) under spinal anesthesia.

排除标准

  • •Patients' refusal
  • •Contraindications to spinal anesthesia or nerve blocks.
  • •History of allergy to the medications used in the study.
  • •Pregnancy.
  • •Significant cognitive impairment.

研究组 & 干预措施

Group A

Experimental

Patients received an ultrasound-guided supra-inguinal fascia iliaca compartment block.

干预措施: Fascia iliaca compartment block (Other)

Group B

Active Comparator

Patients received an ultrasound-guided pericapsular nerve group (PENG) block.

干预措施: Pericapsular nerve group block (Other)

结局指标

主要结局

Number of cases needing rescue doses

时间窗: 24 hours postoperatively

The number of cases needing rescue doses was recorded.

Degree of pain

时间窗: 24 hours postoperatively

Degree of pain was assessed using the Visual Analogue Scale (VAS). VAS is ranging from 0 to 10, where 0 is no pain and 10 is maximum pain. VAS was recorded at 0, 2, 4, 6, 12, 18, and 24 hours postoperatively.

Total amount of nalbuphine consumption

时间窗: 24 hours postoperatively

If the postoperative Visual Analogue Scale (VAS) was greater than 3, an intravenous dose of 5 mg Nalbuphine diluted in 5 mL of saline was administered as needed.

次要结局

  • Postoperative ambulation(24 hours postoperatively)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Diaaeldin Badr Aboelnile

Lecturer of Anesthesia

Ain Shams University

研究点 (1)

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