Prevalence of Carotid Artery Stenosis and Abdominal Aortic Aneurysms in Brussels: a Population-based Screening Study.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 3,286
- 试验地点
- 2
- 主要终点
- Risk factors associated with CAS and AAA among 60+ Brussels inhabitants.
研究概览
简要总结
Both abdominal aortic aneurysm (AAA) and carotid artery stenosis (CAS) are frequent clinical entities, with major morbidity and mortality.
This project obtains robust data on the prevalence of AAA and CAS in the Brussels Capital Region. Using duplex ultrasound, a low invasive examination, we want to obtain information on a vast sample of men and women of the Brussels capital region, starting at the age of 60. With these data we can have a far better view on the Belgian situation of these two main vascular clinical entities. The data can provide insights on if, and how, Belgian public health policy can be improved concerning AAA and CAS.
详细描述
A population-based screening study to determine the prevalence of carotid artery stenosis (CAS) and abdominal aortic aneurysms (AAA) in the Brussels Capital Region.
The study population is the 60+ inhabitants of the Brussels capital region; recruitment of 4680 subjects. Using duplex ultrasound, a low invasive examination, information is obtained on the abdominal aortic diameter and the degree of stenosis of the carotid bifurcation.
The objective is to determine not only the prevalence of, but also the risk factors associated with CAS and AAA among 60+ Brussels inhabitants. To collect these data, a questionnaire is made including demographic features, associated risk factors, but also previous treatment for AAA or CAS and the current medication of the subject.
Examination is done by one-time duplex ultrasound to perform a diameter measurement of the abdominal aorta and determine the degree of stenosis of the carotid arteries.
Data collection will be done in an electronic case report form, and statistical analysis will be done by a multi-variable logistic regression model.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Screening
- 盲法
- None
入排标准
- 年龄范围
- 60 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Candidate is at least 60 years old.
- •Candidate lives in Brussels capital region at the time of study participation.
- •Candidate must sign and date the informed consent form prior to study participation.
排除标准
- •Candidate is suspected of being unable to comply with the study protocol.
结局指标
主要结局
Risk factors associated with CAS and AAA among 60+ Brussels inhabitants.
时间窗: Screening period of 2 years
Determine the risk factors via a questionnaire: * Smoking (ex - current - none) * Hypertension (medical history - current) * Coronary Artery Disease (history of angina pectoris or myocardial infarction) * Diabetes Mellitus (history of diet or medically-treated diabetes - type I or II) * History of Cerebro Vascular Disease (stroke or TIA) * Family (parents/siblings) history (AAA, CVD, ...) * Hypercholesterolemia * Body weight \& length (BMI) * COPD
Prevalence of CAS and AAA among 60+ Brussels inhabitants.
时间窗: Screening period of 2 years
Determine the prevalence using echo duplex screening.
次要结局
未报告次要终点
研究者
Erik Debing
Head of the Department of Vascular Surgery Professor Doctor Erik Debing
Universitair Ziekenhuis Brussel