Multicenter Myocardial Viability Trial
Completed
- Conditions
- Coronary Artery Disease
- Registration Number
- NCT00661232
- Lead Sponsor
- CHI St. Luke's Health, Texas
- Brief Summary
The purpose of this study is to test the hypothesis of whether contrast enhanced Magnetic Resonance Imaging can be used to predict improvement of the wall motion in regions of the heart with abnormal movement following bypass surgery or percutaneous angioplasty in various institutions across three continents.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 235
Inclusion Criteria
- Age: > 21 years and < 85 years
- Sinus rhythm
- Weight < 120 kg
- LVEF > 30%
- Wall motion abnormality on Echo. or LV-gram
- Scheduled for revascularization - Angioplasty/Stent or CABG - within 30 days
Exclusion Criteria
- Resting heart rate > 100 bpm
- Frequent atrial or ventricular ectopy
- Severe aortic stenosis or HOCM
- Unstable angina
- Myocardial infarction within 14 days
- Active congestive heart failure
- Pregnancy
- Known allergy to gadolinium
- Contraindication to MRI
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To examine whether the extent of irreversible myocardial injury as assessed by Delayed Enhancement Magnetic Resonance Imaging can predict the extent of functional recovery after revascularization in patients with chronic coronary artery disease (CAD). 36 months
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (7)
St. Luke's Episcopal Hospital
🇺🇸Houston, Texas, United States
Siriraj Hospital
🇹ðŸ‡Bangkoknoi, Bangkok, Thailand
Cardiac MRI Unit
🇬🇧Leeds, United Kingdom
St. Luke's Episcopal Location
🇺🇸Houston, Texas, United States
Skejby University Hospital
🇩🇰Aarhus N, Denmark
Cliniques Universitaires St. Luc
🇧🇪Brussels, Belgium
Hygeia Hospital
🇬🇷Maroussi, Greece