Validation of several formulas for differentiation thalassemia from iron deficiency anemia and proposed TID predictive score

Completed

• Conditions: Microcytic anemia; Microcytic anemia, Thalassemia, Iron deficiency anemia, TID predictive score

• Registration Number: TCTR20210725003
• Lead Sponsor: Chaopraya Yommarat Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2021-06-30
• Study Start: 2021-07-25
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 227

Inclusion Criteria

1 Age more than 15 years old
2 Microcytic anemia: Hemoglobin(Hb) less than 13 g/dl in male or Hemoglobin(Hb) less than 12 g/dl in female with MCV less than 80 fL and
- Iron deficiency anemia was diagnosed by iron study; Serum ferritin (SF) <30 ng/mL and Transferrin saturation (TSAT) < 16 % or
- Thalassemia was diagnosed by Hb typing or PCR for alpha thalassemia
3 Iron study such as Serum feritin, Transferrin Saturation or Hbtyping or PCR for alpha thalassemia were investigated

Exclusion Criteria

1 Patient was received Erythropoiesis stimulating agent
2 Patient was received iron supplement ( oral or intraveonous form)

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Sensitivity assessment of several formulas and11T score for the differentiation between Iron deficiency anemia and Thalassemia June 1, 2015 to September 30, 2020 11Tscore

Secondary Outcome Measures

Name	Time	Method
Specificity and accuracy assessment of several formulas and11T score for the differentiation between Iron deficiency anemia and Thalassemia June 1, 2015 to September 30, 2020 11Tscore,Sensitivity specificity and accuracy assessment of proposed TID predictive score June 1, 2015 to September 30, 2020 TID score