Prospective Use of Computational Cardiac Imaging Analysis to Guide Ventricular Tachycardia Ablation Procedures (AI-VT)
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 入组人数
- 250
- 试验地点
- 1
- 主要终点
- Recurrent ventricular tachycardia
研究概览
简要总结
The purpose of this study is to evaluate the clinical outcomes (clinical efficacy and safety) of using supplemental non-invasive computational ECG and cardiac imaging analysis tools to help guide ablation of ventricular tachycardia.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 21 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age between 21 and 100
- •Evidence of ventricular tachycardia on ECG, telemetry or by CIED interrogation.
排除标准
- 未提供
研究组 & 干预措施
VT ablation guided by supplemental non-invasive computational imaging analysis
The electrophysiologist performing the standard-of-care VT ablation will have access to supplemental arrhythmia targeting/localization information provided by computational non-invasive ECG and/or cardiac CT imaging analysis
干预措施: Computational electrocardiography and cardiac computed tomography mapping (Diagnostic Test)
结局指标
主要结局
Recurrent ventricular tachycardia
时间窗: 1 year
Ventricular tachycardia episodes defined as implantable cardioverter defibrillator (ICD) therapies (anti-tachycardia pacing and shocks)
All-cause death
时间窗: 1 year
次要结局
- Acute hemodynamic decompensation(24 hours post-op)
- Unplanned prolonged ICU upgrade(48 hours)
- acute cerebrovascular accident (embolic)(24 hours post-op)
- acute pericardial tamponade requiring intervention(24 hours post-op)
- vascular complication requiring intervention(24 hours post-op)
研究者
Gordon Ho
Principal Investigator, Cardiac Electrophysiology Physician
University of California, San Diego