NCT00309816已完成3 期
Measurement of the Effect of Sildenafil Citrate (Viagra) on the Hemodynamics of Exercise Tolerance in Advanced Congestive Heart Failure.
适应症
相关药物
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 2
- 主要终点
- Patients will have exercise capacity measured by an exercise stress test before and after one dose of sildenafil.
研究概览
简要总结
The purpose of this study is to determine if sildenafil (Viagra) improves exercise tolerance.
详细描述
Patients will undergo an exercise stress test. One dose of Sildenafil will then be given, followed by a one hour rest period. A repeat exercise stress test will then be repeated.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 18 - 75 Ejection fraction <35% Heart failure limited by fatigue and shortness of breath -
排除标准
- •Inability to exercise. Patients with shortness of breath while resting. Patient requiring intravenous medication. Patients taking the following medications: nitroglycerine pill/patch/paste, isordil and Imdur
结局指标
主要结局
Patients will have exercise capacity measured by an exercise stress test before and after one dose of sildenafil.
次要结局
未报告次要终点
研究者
研究点 (2)
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