ACTRN12621001043820招募中2 期
A phase 2b randomised controlled trial of the renal effects of angiotensin II versus noradrenaline in critically ill patients with vasodilatory shock
适应症
试验速览
- 阶段
- 2 期
- 状态
- 招募中
- 入组人数
- 150
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- All
入选标准
- •Adults aged 18+ years
- •Vasodilatory shock (MAP <65 mmHg)
- •Central venous access and an arterial line present
- •Indwelling urinary catheter
- •Expected to require vasopressor support for at least 24 hours
- •Informed consent provided by the patient or medical treatment decision-maker
排除标准
- •Cardiac surgery patients
- •>24 hours noradrenaline, metaraminol or vasopressin prior to enrolment
- •Chronic haemodialysis or peritoneal dialysis
- •Not expected to receive venous thromboembolism prophylaxis in the next 72 hours
- •Expected survival <24 hours
- •Suspected or confirmed pregnancy
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