Evaluating the effectiveness and cost-effectiveness of integrating mass drug administration for helminth control with seasonal malaria chemoprevention in Ghanaian childre

Not Applicable

Not yet recruiting

• Conditions: Malaria; Neglected Tropical Diseases - Soil Transmitted Helminths and schistosomiasis

• Registration Number: PACTR202312489417172
• Lead Sponsor: ondon School of Hygiene Tropical Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-12-04
• Last Update Posted: 2024-03-04

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 1200

Inclusion Criteria

• Male and female children aged 1-14 years;
• Provision of written informed consent by the parent/caregiver and a positive assent by children aged = 7 years (in line with legal regulations in Ghana);
• Willingness to provide finger prick blood samples, urine, and stool samples;
• Residence in the study area for at least the past six months and willingness to be available in the study area for follow-up about 6 months after enrolment.

Exclusion Criteria

•Acutely ill child at the time of the drug administration;
•A child whose parents/care-givers decline to provide consent;
•A known HIV-positive child receiving co-trimoxazole prophylaxis;
•A child who has received a dose of either Sulphadoxine-pyrimethamine (SP), amodiaquine (AQ), albendazole (ALB) or praziquantel (PZQ) during the previous six months;
•A child with a known allergy to any of SP, AQ, ALB, or PZQ

Study & Design

• Study Type: Interventional
• Study Design: Not specified