Evaluation of Perfusion Index as a determinant of depth of anaesthesia: Correlation with Minimum Alveolar Concentration and Bispectral Index.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 35
- 试验地点
- 1
- 主要终点
- Changes in Perfusion Index and MAC at certain defined time points.
研究概览
简要总结
Purpose of the trial- To find if there is correlation between Perfusion Index, Bispectral Index and Minimum Alveolar Concentration.
Background and findings- After noting baseline Perfusion Index, Bispectral Index and Minimum Alveolar Concentration, heart rate and MAP, standard General Anaesthesia will be administered to the patients. Values of the same parameters are noted at different time points. The results are out and we found that perfusion index and MAC correlate well at certain time points of study.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 50.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA physical status I and II
- •Anticipated duration of surgery 30-120 minutes.
排除标准
- •Patients diagnosed with peripheral artery disease, hypertension, cardiovascular disease.
- •Known conditions affecting peripheral perfusion like coarctation of aorta etc..
- •Patients with obesity, anticipated difficult airway.
- •History of long standing Diabetes mellitus
- •Patients on chronic drug therapy, drug/alcohol abuse
- •Anticipated surgical blood loss>10% of blood volume
- •Pregnant patients.
结局指标
主要结局
Changes in Perfusion Index and MAC at certain defined time points.
时间窗: T0 - (Baseline - after application of monitoring devices) | T1 - Preinduction - after sedation with midazolam and fentanyl) | T2 - Postinduction - after loss of verbal response | T3 - Just prior to inserting SGD | T4 - During airway manipulation | T5 - At time of surgical incision | T6 - Fifteen minutes after surgical incision. | T7 - During recovery; at 0.5 MAC | T8 - During recovery; at 0.3 MAC | T9 - At the return of response to verbal commands.
次要结局
- Changes in Bispectral Index, Heart Rate, Mean arterial pressure(T0 - (Baseline - after application of monitoring devices))