ISRCTN65690030已完成未知
Effects of varenicline and cognitive bias modification on neural response to smoking-related cues
niversity of Bristol (UK)0 个研究点目标入组 72 人开始时间: 2014年1月30日最近更新:
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 72
研究概览
简要总结
- 2014 protocol in: http://www.ncbi.nlm.nih.gov/pubmed/25294104 2. 2014 results in https://www.ncbi.nlm.nih.gov/pubmed/25294104 (added 18/01/2019)
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Smokes > 10 manufactured cigarettes or > 15 roll up cigarettes per day
- •2. Smokes within one hour of waking
- •3. Aged between 18 and 40 years
- •4. Able to attend all of the study session
- •5. English as first language or equivalent level of fluency
排除标准
- •1. Female volunteers who are pregnant or breast feeding
- •2. Female volunteers not using adequate contraception
- •3. Volunteers who do not currently have a GP
- •4. Current or previous substance or alcohol misuse or dependence [other than nicotine]
- •5. Alcohol use in excess of 35 Units/week if female or 50 Units/week if male
- •6. Caffeine use = 8 cups per day
- •7. Significant current or past psychiatric illness (Axis 1 or 2 psychiatric diagnoses) as diagnosed by a psychiatrist
- •8. Clinically significant abnormality including cardiology risk factors and history of arrhythmia (as assessed by self-report)
- •9. Ongoing use of medication (i.e. intake of any medication within 8 weeks of study, with exception of local treatment and occasional paracetamol or non-steroidal anti-inflammatory drugs, e.g., aspirin or ibuprofen)
- •10. Smokers actively trying to give up smoking during the study period
- •11. Uncorrected visual impairment (including colour-blindness)
- •12. Uncorrected auditory impairment
- •13. Condition that makes MRI scanning unsafe (e.g. metallic implants; history of metal-working)
- •14. Unable to tolerate scanning environment (as established during a short anatomical MRI scan on day 0)
- •15. Hypersensitivity to Champix
研究者
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