Paravertebral Block Versus Thoracic Epidural Analgesia in Patients Undergoing Video Assisted Lung Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 94
- 试验地点
- 1
- 主要终点
- Time in minutes total time at the operating ward
研究概览
简要总结
Thoracic epidural analgesia (TEA) is the basic method of analgesia in patients undergoing pulmonary lobectomy. TEA is considered to be a safe and thoroughly investigated method of pain relief that rarely causes serious complications. However, blocking the nerves as they emerge from the spinal column (paravertebral block, PVB) may represent an alternative method with some potential benefits. In this study, TEA and PVB will be compared for patients undergoing pulmonary lobectomy by video assisted thoracoscopic surgery. The aim of the study is to test the hypothesis, that PVB is a time-saving procedure compared with TEA on the day of surgery and that PVB is as efficient in postoperative pain reduction as TEA.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with lung cancer in stage 1 or 2 who are accepted for VATS-lobectomy
- •Exclusion Criteria, preoperative:
- •Patients who do not wish to participate
- •Patients with:
- •suspicion of ingrowth in the thoracic wall.
- •marginal lung function.
- •kidney failure.
- •chronic pains and/ or daily use of opioids.
- •cognitive, visual and / or linguistic dysfunction.
- •allergies to drugs used in the paravertebral block or the thoracic epidural analgesia.
- •Exclusion Criteria, Per- and postoperative
- •conversion from VATS to thoractomy.
- •unsuccessful admission of thoracic epidural analgesia
- •unsuccessful admission of paravertebral block
- •postoperative respiratory treatment
- •postoperative delirium Patients who for various reasons are not able to self-report pain after surgery.
- •Patients who wish to withdraw from the study
排除标准
- 未提供
研究组 & 干预措施
Thoracic epidural analgesia
Standard thoracic epidurals preoperatively at the dag of surgery.
干预措施: Thoracic epidural (Drug)
Paravertebral block
Paravertebral block inserted at the end of the operation by the surgeons
干预措施: Paravertebral block (Drug)
结局指标
主要结局
Time in minutes total time at the operating ward
时间窗: 1 hour
Pain intensity during hospitalization: Numerical Rating Scale (NRS)
时间窗: Up to 12 months after surgery
using the Numerical Rating Scale (NRS) in predetermined time intervals after the operation
次要结局
- Hospital length of stay in days(until discharge from hospital (max 1 month))