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临床试验/NCT04788030
NCT04788030已完成不适用

Outcome After Reconstruction of 43 Digital Nerve Lesions With Muscle-in-Vein Conduits

BG Trauma Center Tuebingen0 个研究点目标入组 37 人开始时间: 2008年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
37
主要终点
Two-point discrimination

研究概览

简要总结

Muscle-in-vein conduits (MVCs) provide an alternative for bridging digital nerve defects when tension-free suture is not possible. Low donor site morbidity and absence of additional costs are favorable advantages compared to autografts or conduits. 37 patients with 43 defects of proper palmar digital nerves were retrospectively enrolled. Primary repair by MVCs was performed in 22 cases while 21 underwent secondary reconstruction. Recovery of sensibility was assessed by static and moving two-point discrimination (2PDs, 2PDm) and Semmes-Weinstein monofilaments (SWM). Results were compared with contralateral side serving as intraindividual control. Outcome data were stratified according to international guidelines and evaluated for differences in terms of age, gap length, time of reconstruction and concomitant injuries.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Retrospective

入排标准

年龄范围
6 Years 至 72 Years(Child, Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients with reconstruction of digital nerves with muscle-in-vein conduits

排除标准

  • Subtotal or total amputations
  • pre-existing neurological disorders (e.g. polyneuropathy)
  • symptoms of nerve entrapment

结局指标

主要结局

Two-point discrimination

时间窗: Six months after reconstruction or later

Semmes-Weinstein-Monofilament test

时间窗: Six months after reconstruction or later

次要结局

  • Gap length(Baseline)
  • Concomitant injuries(Baseline)
  • Time of reconstruction(Baseline)
  • Age(Baseline)

研究者

发起方
BG Trauma Center Tuebingen
申办方类型
Other
责任方
Principal Investigator
主要研究者

PD Dr. Theodora Wahler

Chief of the Department of Hand, Plastic and Aesthetic Surgery, medius Hospital Nürtingen

BG Trauma Center Tuebingen

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