MedPath

Reconstruction of Digital Nerve Lesions With Muscle-in-Vein Conduits

Completed
Conditions
Peripheral Nerve Injury Upper Limb
Interventions
Other: Nerve reconstruction
Registration Number
NCT04788030
Lead Sponsor
BG Trauma Center Tuebingen
Brief Summary

Muscle-in-vein conduits (MVCs) provide an alternative for bridging digital nerve defects when tension-free suture is not possible. Low donor site morbidity and absence of additional costs are favorable advantages compared to autografts or conduits. 37 patients with 43 defects of proper palmar digital nerves were retrospectively enrolled. Primary repair by MVCs was performed in 22 cases while 21 underwent secondary reconstruction. Recovery of sensibility was assessed by static and moving two-point discrimination (2PDs, 2PDm) and Semmes-Weinstein monofilaments (SWM). Results were compared with contralateral side serving as intraindividual control. Outcome data were stratified according to international guidelines and evaluated for differences in terms of age, gap length, time of reconstruction and concomitant injuries.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
37
Inclusion Criteria
  • Patients with reconstruction of digital nerves with muscle-in-vein conduits
Exclusion Criteria
  • Subtotal or total amputations
  • pre-existing neurological disorders (e.g. polyneuropathy)
  • symptoms of nerve entrapment

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Digital nerve reconstruction with muscle-in-vein conduitsNerve reconstruction-
Primary Outcome Measures
NameTimeMethod
Two-point discriminationSix months after reconstruction or later
Semmes-Weinstein-Monofilament testSix months after reconstruction or later
Secondary Outcome Measures
NameTimeMethod
Gap lengthBaseline
Concomitant injuriesBaseline
AgeBaseline
Time of reconstructionBaseline
© Copyright 2025. All Rights Reserved by MedPath