Short- and long-term effects of oxytocin on empathy in autistic male adults.
Completed
- Conditions
- autisme spectrum stoornis / antisociale persoonlijkheidantisocial personality disorderautism10010118
- Registration Number
- NL-OMON36342
- Lead Sponsor
- niversitair Medisch Centrum Groningen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 52
Inclusion Criteria
male, age 18 through 30 years; IQ > 80; patients: meeting DSM-IV criteria for Autism Spectrum Disorder
Exclusion Criteria
alcohol or drug dependence; free of psychotropic medication or neuroleptics
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>In the short-term experimental trial, our primary outcome measures shall be the<br /><br>ERP and cardiac responses in the various IAPS picture conditions. These<br /><br>neurophysiological responses reflect fast changes in the activity of the<br /><br>neurobiological systems involved in emotion processing.<br /><br>Another outcome measure shall be the score on a questionnaire assessing<br /><br>(short-term changing) state-related anxiety. Scores of this measure shall be<br /><br>obtained from the questionnaire being completed shortly before and about 15<br /><br>minutes after oxytocin / placebo administration.</p><br>
- Secondary Outcome Measures
Name Time Method